An investigation into the tourism and hospitality scholarly activity currently being undertaken in Irish higher education institutions

The purpose of this article is to describe the tourism and hospitality scholarly activity currently taking place in Irish higher education (HE) institutions. A number of approaches to tourism and hospitality research are identified in the literature. In order to understand the policy and practice within the Irish HE sector, qualitative research was conducted through a survey of tourism and hospitality academics and researchers within Irish HE institutions. The findings suggest that tourism and hospitality scholarly activity in Ireland is being carried out in many ways, including through joint research projects between Irish HE institutions and industry. This is a positive step towards achieving research and industry harmony. The development of stand-alone research centres within these institutions can also promote and attract funding for tourism and hospitality research activities

Anthropic Estimates of the Charge and Mass of the Proton

By combining a renormalization group argument relating the charge e and mass m of the proton by e^2 ln m ~ 0.1 pi (in Planck units) with the Carter-Carr-Rees anthropic argument that gives an independent approximate relation m ~ e^20 between these two constants, both can be crudely estimated. These equations have the factor of 0.1 pi and the exponent of 20 which depend upon known discrete parameters (e.g., the number of generations of quarks and leptons, and the number of spatial dimensions), but they contain NO continuous observed parameters. Their solution gives the charge of the proton correct to within about 8%, though the mass estimate is off by a factor of about 1000 (16% error on a logarithmic scale). When one adds a fudge factor of 10 previously given by Carr and Rees, the agreement for the charge is within about 2%, and the mass is off by a factor of about 3 (2.4% error on a logarithmic scale). If this 10 were replaced by 15, the charge agrees within 1.1% and the mass itself agrees within 0.7%.Comment: 12 pages, LaTe

Stigma and treatment of eating disorders in Ireland: healthcare professionals' knowledge and attitudes

Objectives: This study examines aspects of health professionals’ knowledge and attitudes about eating disorders (EDs) , which might impede the effective detection or treatment of EDs in Ireland. Methods: 1,916 health professionals were invited to participate in a web-based survey. Participants were randomly allocated to view one of five vignettes depicting a young person with symptoms consistent with Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, Depression or Type 1 Diabetes. Study-specific questions examined participants’ responses to the vignettes and ED knowledge and experience

Eating disorder literacy and stigmatising attitudes towards anorexia, bulimia and binge eating disorder among adolescents

Little research has investigated adolescents’ understanding of eating disorders (EDs) or attitudes towards people affected by EDs. This impedes the development of targeted health promotion interventions. In the current study, 290 adolescents viewed a vignette depicting a target with either Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, Depression or Type 1 Diabetes. Subsequent questionnaires assessed understanding of and attitudes towards the disorder described . Adolescents recognised the symptoms of depression significantly more frequently than any ED. Relative to depression and Type 1 diabetes, participants held targets with EDs more personally responsible for their illness and ascribed them more negative personality characteristics. The data revealed a particularly unfavourable view of Binge Eating Disorder, which was conceptualised as a failure of self-discipline rather than a medical condition. The results confirm previous findings that EDs are more stigmatised than other mental or physical health conditions and extend the findings to an adolescent cohort

A General Cause Based Methodology for Analysis of Dependent Failures in System Risk and Reliability Assessments

Traditional parametric Common Cause Failure (CCF) models quantify the soft dependencies between component failures through the use of empirical ratio relationships. Furthermore CCF modeling has been essentially restricted to identical components in redundant formations. While this has been advantageous in allowing the prediction of system reliability with little or no data, it has been prohibitive in other applications such as modeling the characteristics of a system design or including the characteristics of failure when assessing the risk significance of a failure or degraded performance event (known as an event assessment). This dissertation extends the traditional definition of CCF to model soft dependencies between like and non-like components. It does this through the explicit modeling of soft dependencies between systems (coupling factors) such as sharing a maintenance team or sharing a manufacturer. By modeling the soft dependencies explicitly these relationships can be individually quantified based on the specific design of the system and allows for more accurate event assessment given knowledge of the failure cause. Since the most data informed model in use is the Alpha Factor Model (AFM), it has been used as the baseline for the proposed solutions. This dissertation analyzes the US Nuclear Regulatory Commission's Common Cause Failure Database event data to determine the suitability of the data and failure taxonomy for use in the proposed cause-based models. Recognizing that CCF events are characterized by full or partial presence of "root cause" and "coupling factor" a refined failure taxonomy is proposed which provides a direct link between the failure cause category and the coupling factors. This dissertation proposes two CCF models (a) Partial Alpha Factor Model (PAFM) that accounts for the relevant coupling factors based on system design and provide event assessment with knowledge of the failure cause, and (b)General Dependency Model (GDM),which uses Bayesian Network to model the soft dependencies between components. This is done through the introduction of three parameters for each failure cause that relate to component fragility, failure cause rate, and failure cause propagation probability

Simulation of the Elastic Properties of Reinforced Kevlar-Graphene Composites

The compressive strength of unidirectional fiber composites in the form of Kevlar yarn with a thin outer layer of graphene was investigated and modeled. Such fiber structure may be fabricated by using a strong chemical bond between Kevlar yarn and graphene sheets. Chemical functionalization of graphene and Kevlar may achieved by modification of appropriate surface-bound functional (e.g., carboxylic acid) groups on their surfaces. In this report we studied elastic response to unidirectional in-plane applied load with load peaks along the diameter. The 2D linear elasticity model predicts that significant strengthening occurs when graphene outer layer radius is about 4 % of kevlar yarn radius. The polymer chains of Kevlar are linked into locally planar structure by hydrogen bonds across the chains, with transversal strength considerably weaker than longitudinal one. This suggests that introducing outer enveloping layer of graphene, linked to polymer chains by strong chemical bonds may significantly strengthen Kevlar fiber with respect to transversal deformations

Bronchoabsorption; a novel bronchoscopic technique to improve biomarker sampling of the airway

BACKGROUND: Current techniques used to obtain lung samples have significant limitations and do not provide reproducible biomarkers of inflammation. We have developed a novel technique that allows multiple sampling methods from the same area (or multiple areas) of the lung under direct bronchoscopic vision. It allows collection of mucosal lining fluid and bronchial brushing from the same site; biopsy samples may also be taken. The novel technique takes the same time as standard procedures and can be conducted safely. METHODS: Eight healthy smokers aged 40–65 years were included in this study. An absorptive filter paper was applied to the bronchial mucosa under direct vision using standard bronchoscopic techniques. Further samples were obtained from the same site using bronchial brushings. Bronchoalveolar lavage (BAL) was obtained using standard techniques. Chemokine (C-C Motif) Ligand 20 (CCL20), CCL4, CCL5, Chemokine (C-X-C Motif) Ligand 1 (CXCL1), CXCL8, CXCL9, CXCL10, CXCL11, Interleukin 1 beta (IL-1β), IL-6, Vascular endothelial growth factor (VEGF), Matrix metalloproteinase 8 (MMP-8) and MMP-9 were measured in exudate and BAL. mRNA was collected from the bronchial brushings for gene expression analysis. RESULTS: A greater than 10 fold concentration of all the biomarkers was detected in lung exudate in comparison to BAL. High yield of good quality RNA with RNA integrity numbers (RIN) between 7.6 and 9.3 were extracted from the bronchial brushings. The subset of genes measured were reproducible across the samples and corresponded to the inflammatory markers measured in exudate and BAL. CONCLUSIONS: The bronchoabsorption technique as described offers the ability to sample lung fluid direct from the site of interest without the dilution effects caused by BAL. Using this method we were able to successfully measure the concentrations of biomarkers present in the lungs as well as collect high yield mRNA samples for gene expression analysis from the same site. This technique demonstrates superior sensitivity to standard BAL for the measurement of biomarkers of inflammation. It could replace BAL as the method of choice for these measurements. This method provides a systems biology approach to studying the inflammatory markers of respiratory disease progression. TRIAL REGISTRATION: NHS Health Research Authority (13/LO/0256)

The Adjudication and Enforcement of Rights After Brexit

This report records the inaugural meeting and roundtable of the Brexit and Rights Engagement Network (BREN) on Tuesday 3rd July 2018 at Edinburgh Law School. Attendees at the roundtable included network members, fellow academics, representatives of the Scottish Parliament, the Scottish Government, the Scottish Human Rights Commission, the Equality and Human Rights Commission, the legal professions, and NGOs. Two years after the EU Referendum and only a few days after the European Union (Withdrawal) Act 2018 (the 2018 Act) receiving Royal Assent, the Brexit and Rights Engagement Network met for the first time. The purpose of the roundtable was to ignite debate amongst legal scholars and policy makers, and others working in a rights environment relating to interpretation, adjudication and enforcement of rights in the lead up to, and following “Brexit Day,” (March 29, 2019). This report is split into two sections, Part A will consider the adjudication of EU rights, but also their enforcement under the 2018 Act and the Withdrawal Agreement, whilst ‘options for the future’ will be broached in Part B

Neutrino Breakup of A=3 Nuclei in Supernovae

We extend the virial equation of state to include 3H and 3He nuclei, and predict significant mass-three fractions near the neutrinosphere in supernovae. While alpha particles are often more abundant, we demonstrate that energy transfer cross-sections for muon and tau neutrinos at low densities are dominated by breakup of the loosely-bound 3H and 3He nuclei. The virial coefficients involving A=3 nuclei are calculated directly from the corresponding nucleon-3H and nucleon-3He scattering phase shifts. For the neutral-current inelastic cross-sections and the energy transfer cross sections, we perform ab-initio calculations based on microscopic two- and three-nucleon interactions and meson-exchange currents.Comment: 6 pages, 2 figures, minor additions, to appear in Phys. Rev.